LL-37 is a cationic antimicrobial peptide derived from the C-terminal portion of the human cathelicidin precursor protein, hCAP18. It plays a multifaceted role in innate immunity by exhibiting broad-spectrum antimicrobial activity and modulating inflammatory responses. LL-37 is known to influence wound healing, cellular migration, and tissue remodeling, while also regulating the activation and recruitment of various immune cells. Its interaction with microbial membranes and host receptors contributes to both direct pathogen defense and immune system modulation.
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